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Network-wide thermodynamic constraints shape NAD(P)H cofactor specificity of biochemical reactions
The ubiquitous coexistence of the redox cofactors NADH and NADPH is widely considered to facilitate an efficient operation of cellular redox metabolism. However, it remains unclear what shapes the NAD(P)H specificity of specific redox reactions. Here, we present a computational framework to analyze...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400544/ https://www.ncbi.nlm.nih.gov/pubmed/37537166 http://dx.doi.org/10.1038/s41467-023-40297-8 |