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Label-free measurement of antimicrobial peptide interactions with lipid vesicles and nanodiscs using microscale thermophoresis

One strategy to combat antimicrobial resistance is the discovery of new classes of antibiotics. Most antibiotics will at some point interact with the bacterial membrane to either interfere with its integrity or to cross it. Reliable and efficient tools for determining the dissociation constant for m...

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Detalles Bibliográficos
Autores principales: Rainsford, Philip, Rylandsholm, Fredrik G., Jakubec, Martin, Silk, Mitchell, Juskewitz, Eric, Ericson, Johanna U., Svendsen, John-Sigurd, Engh, Richard A., Isaksson, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400562/
https://www.ncbi.nlm.nih.gov/pubmed/37537266
http://dx.doi.org/10.1038/s41598-023-39785-0