Smurf1 and Smurf2 mediated polyubiquitination and degradation of RNF220 suppresses Shh-group medulloblastoma

Sonic hedgehog (Shh)-group medulloblastoma (MB) (Shh-MB) encompasses a clinically and molecularly distinct group of cancers originating from the developing nervous system with aberrant high Shh signaling as a causative driver. We recently reported that RNF220 is required for sustained high Shh signa...

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Detalles Bibliográficos
Autores principales: Li, Yuwei, Wang, Huishan, Sun, Bin, Su, Guifeng, Cang, Yu, Zhao, Ling, Zhao, Shuhua, Li, Yan, Mao, Bingyu, Ma, Pengcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400574/
https://www.ncbi.nlm.nih.gov/pubmed/37537194
http://dx.doi.org/10.1038/s41419-023-06025-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400574/
https://www.ncbi.nlm.nih.gov/pubmed/37537194
http://dx.doi.org/10.1038/s41419-023-06025-2

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