Diagnostic yield and clinical relevance of expanded germline genetic testing for nearly 7000 suspected HBOC patients

Here we report the results of a retrospective germline analysis of 6941 individuals fulfilling the criteria necessary for genetic testing of hereditary breast- and ovarian cancer (HBOC) according to the German S3 or AGO Guidelines. Genetic testing was performed by next-generation sequencing using 12...

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Detalles Bibliográficos
Autores principales: Henkel, Jan, Laner, Andreas, Locher, Melanie, Wohlfrom, Tobias, Neitzel, Birgit, Becker, Kerstin, Neuhann, Teresa, Abicht, Angela, Steinke-Lange, Verena, Holinski-Feder, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400578/
https://www.ncbi.nlm.nih.gov/pubmed/37188824
http://dx.doi.org/10.1038/s41431-023-01380-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400578/
https://www.ncbi.nlm.nih.gov/pubmed/37188824
http://dx.doi.org/10.1038/s41431-023-01380-2

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