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Droplet-based bisulfite sequencing for high-throughput profiling of single-cell DNA methylomes

The genome-wide DNA methylation profile, or DNA methylome, is a critical component of the overall epigenomic landscape that modulates gene activities and cell fate. Single-cell DNA methylomic studies offer unprecedented resolution for detecting and profiling cell subsets based on methylomic features...

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Detalles Bibliográficos
Autores principales: Zhang, Qiang, Ma, Sai, Liu, Zhengzhi, Zhu, Bohan, Zhou, Zirui, Li, Gaoshan, Meana, J. Javier, González-Maeso, Javier, Lu, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400590/
https://www.ncbi.nlm.nih.gov/pubmed/37537185
http://dx.doi.org/10.1038/s41467-023-40411-w