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Molecular insights into Spindlin1-HBx interplay and its impact on HBV transcription from cccDNA minichromosome

Molecular interplay between host epigenetic factors and viral proteins constitutes an intriguing mechanism for sustaining hepatitis B virus (HBV) life cycle and its chronic infection. HBV encodes a regulatory protein, HBx, which activates transcription and replication of HBV genome organized as cova...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Yao, Qiyan, Su, Xiaonan, Deng, Yafang, Yang, Mo, Peng, Bo, Zhao, Fan, Du, Chao, Zhang, Xiulan, Zhu, Jinsong, Wang, Daliang, Li, Wenhui, Li, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400593/
https://www.ncbi.nlm.nih.gov/pubmed/37537164
http://dx.doi.org/10.1038/s41467-023-40225-w