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Simultaneously discovering the fate and biochemical effects of pharmaceuticals through untargeted metabolomics

Untargeted metabolomics is an established approach in toxicology for characterising endogenous metabolic responses to xenobiotic exposure. Detecting the xenobiotic and its biotransformation products as part of the metabolomics analysis provides an opportunity to simultaneously gain deep insights int...

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Detalles Bibliográficos
Autores principales: Bowen, Tara J., Southam, Andrew D., Hall, Andrew R., Weber, Ralf J. M., Lloyd, Gavin R., Macdonald, Ruth, Wilson, Amanda, Pointon, Amy, Viant, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400635/
https://www.ncbi.nlm.nih.gov/pubmed/37537184
http://dx.doi.org/10.1038/s41467-023-40333-7