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A neural-mechanistic hybrid approach improving the predictive power of genome-scale metabolic models
Constraint-based metabolic models have been used for decades to predict the phenotype of microorganisms in different environments. However, quantitative predictions are limited unless labor-intensive measurements of media uptake fluxes are performed. We show how hybrid neural-mechanistic models can...
Autores principales: | Faure, Léon, Mollet, Bastien, Liebermeister, Wolfram, Faulon, Jean-Loup |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400647/ https://www.ncbi.nlm.nih.gov/pubmed/37537192 http://dx.doi.org/10.1038/s41467-023-40380-0 |
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