Inhibition of p38 ameliorates axonal loss with modulation of autophagy in TNF-induced optic nerve damage

PURPOSE: A relationship between p38 and autophagy remains debated. The aim of the current study is to investigate whether an inhibitor of p38 prevents axon loss induced by TNF and whether it affects autophagy. METHODS: Rats were given intravitreal injection of TNF, TNF plus SB203580, a p38 inhibitor...

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Detalles Bibliográficos
Autores principales: Sase, Kana, Tsukahara, Chihiro, Fujita, Naoki, Arizono, Ibuki, Otsubo, Mizuki, Kitaoka, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400678/
https://www.ncbi.nlm.nih.gov/pubmed/37062014
http://dx.doi.org/10.1007/s10792-023-02706-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400678/
https://www.ncbi.nlm.nih.gov/pubmed/37062014
http://dx.doi.org/10.1007/s10792-023-02706-1

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