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Inhibition of p38 ameliorates axonal loss with modulation of autophagy in TNF-induced optic nerve damage
PURPOSE: A relationship between p38 and autophagy remains debated. The aim of the current study is to investigate whether an inhibitor of p38 prevents axon loss induced by TNF and whether it affects autophagy. METHODS: Rats were given intravitreal injection of TNF, TNF plus SB203580, a p38 inhibitor...
Autores principales: | Sase, Kana, Tsukahara, Chihiro, Fujita, Naoki, Arizono, Ibuki, Otsubo, Mizuki, Kitaoka, Yasushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400678/ https://www.ncbi.nlm.nih.gov/pubmed/37062014 http://dx.doi.org/10.1007/s10792-023-02706-1 |
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