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PARP2 promotes inflammation in psoriasis by modulating estradiol biosynthesis in keratinocytes

ABSTRACT: Poly(ADP-ribose) polymerase 2 (PARP2) alongside PARP1 are responsible for the bulk of cellular PARP activity, and they were first described as DNA repair factors. However, research in past decades implicated PARPs in biological functions as diverse as the regulation of cellular energetics,...

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Detalles Bibliográficos
Autores principales: Antal, Dóra, Pór, Ágnes, Kovács, Ilona, Dull, Katalin, Póliska, Szilárd, Ujlaki, Gyula, Demény, Máté Ágoston, Szöllősi, Attila Gábor, Kiss, Borbála, Szegedi, Andrea, Bai, Péter, Szántó, Magdolna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400701/
https://www.ncbi.nlm.nih.gov/pubmed/37351597
http://dx.doi.org/10.1007/s00109-023-02338-z