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Genetic and pharmacological inhibition of METTL3 alleviates renal fibrosis by reducing EVL m6A modification through an IGF2BP2‐dependent mechanism

BACKGROUND: N (6)‐methyladenosine (m6A) is of great importance in renal physiology and disease progression, but its function and mechanism in renal fibrosis remain to be comprehensively and extensively explored. Hence, this study will explore the function and potential mechanism of critical regulato...

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Detalles Bibliográficos
Autores principales: Ni, Wei‐Jian, Zhou, Hong, Lu, Hao, Ma, Nan‐Nan, Hou, Bing‐Bing, Li, Wei, Kong, Fan‐Xu, Yu, Ju‐Tao, Hou, Rui, Jin, Juan, Wen, Jia‐Gen, Zhang, Tao, Meng, Xiao‐Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400756/
https://www.ncbi.nlm.nih.gov/pubmed/37537731
http://dx.doi.org/10.1002/ctm2.1359