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Association between organic cation transporter genetic polymorphisms and metformin response and intolerance in T2DM individuals: a systematic review and meta-analysis

BACKGROUND: Variants in organic cation transporter (OCT) genes play a crucial role in metformin pharmacokinetics and are critical for diabetes treatment. However, studies investigating the effect of OCT genetic polymorphisms on metformin response have reported inconsistent results. This review and m...

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Detalles Bibliográficos
Autores principales: Peng, Aiyu, Gong, Chunmei, Xu, Yuanfei, Liang, Xiongshun, Chen, Xiaoping, Hong, Wenxu, Yan, Junxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400771/
https://www.ncbi.nlm.nih.gov/pubmed/37546319
http://dx.doi.org/10.3389/fpubh.2023.1183879