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Tumor targeting and therapeutic assessments of RNA nanoparticles carrying α9-nAChR aptamer and anti-miR-21 in triple-negative breast cancers

Triple-negative breast cancer (TNBC) is highly aggressive with a poor prognosis because of a lack of cell markers as drug targets. α9-Nicotinic acetylcholine receptor (nAChR) is expressed abundantly in TNBC; thus, it is a valuable biomarker for TNBC detection and treatment. In this study, we utilize...

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Detalles Bibliográficos
Autores principales: Liao, You-Cheng, Cheng, Tzu-Chun, Tu, Shih-Hsin, Chang, Jungshan, Guo, Peixuan, Chen, Li-Ching, Ho, Yuan-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400867/
https://www.ncbi.nlm.nih.gov/pubmed/37547295
http://dx.doi.org/10.1016/j.omtn.2023.07.013