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Trans-acting aptazyme for conditional gene knockdown in eukaryotic cells

Trans-acting hammerhead ribozyme inherits the advantages of being the smallest and best-characterized RNA-cleaving ribozyme, offering high modularity and the ability to cleave any desired sequence without the aid of any protein, as long as the target sequence contains a cleavage site. However, achie...

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Detalles Bibliográficos
Autores principales: Zhou, Shan, Chen, Meiyi, Yuan, Yi, Xu, Yan, Pu, Qinlin, Ai, Xilei, Liu, Shuai, Du, Feng, Huang, Xin, Dong, Juan, Cui, Xin, Tang, Zhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400872/
https://www.ncbi.nlm.nih.gov/pubmed/37547296
http://dx.doi.org/10.1016/j.omtn.2023.07.014