A conserved 3D pattern in a Streptococcus pyogenes M protein immunogen elicits M-type crossreactivity

Coiled coil–forming M proteins of the widespread and potentially deadly bacterial pathogen Streptococcus pyogenes (strep A) are immunodominant targets of opsonizing antibodies. However, antigenic sequence variability of M proteins into >220 M types, as defined by their hypervariable regions (HVRs...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Kuei-Chen, Kuliyev, Eziz, Nizet, Victor, Ghosh, Partho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400905/
https://www.ncbi.nlm.nih.gov/pubmed/37390991
http://dx.doi.org/10.1016/j.jbc.2023.104980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400905/
https://www.ncbi.nlm.nih.gov/pubmed/37390991
http://dx.doi.org/10.1016/j.jbc.2023.104980

Ejemplares similares