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Anabolic phenotype in cartilage-specific mitogen-inducible gene-6 knockout mice is independent of transforming growth factor-α
BACKGROUND/OBJECTIVE: Osteoarthritis (OA) is a whole joint disorder with no disease modifying treatment currently available. The Epidermal Growth Factor Receptor (EGFR) signaling pathway plays an important role in cartilage/bone development and its ligand transforming growth factor-α (TGFα) is upreg...
Autores principales: | Hadzic, Ermina, To, Bethia, Pest, Michael A., Qin, Ling, Beier, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400912/ https://www.ncbi.nlm.nih.gov/pubmed/37547183 http://dx.doi.org/10.1016/j.ocarto.2023.100387 |
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