Molecular dynamics simulations reveal the hidden EF-hand of EF-SAM as a possible key thermal sensor for STIM1 activation by temperature

Intracellular calcium signaling is essential for many cellular processes, including store-operated Ca(2+) entry (SOCE), which is initiated by stromal interaction molecule 1 (STIM1) detecting endoplasmic reticulum (ER) Ca(2+) depletion. STIM1 is also activated by temperature independent of ER Ca(2+)...

Descripción completa

Detalles Bibliográficos
Autores principales: Neamtu, Andrei, Serban, Dragomir N., Barritt, Greg J., Isac, Dragos Lucian, Vasiliu, Tudor, Laaksonen, Aatto, Serban, Ionela Lacramioara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400917/
https://www.ncbi.nlm.nih.gov/pubmed/37380078
http://dx.doi.org/10.1016/j.jbc.2023.104970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400917/
https://www.ncbi.nlm.nih.gov/pubmed/37380078
http://dx.doi.org/10.1016/j.jbc.2023.104970

Ejemplares similares