The ATR inhibitor VE-821 increases the sensitivity of gastric cancer cells to cisplatin

BACKGROUND: Chemoresistance is a common event after cancer chemotherapy, including gastric cancer (GC). Cisplatin has been reported to induce the DNA damage response (DDR), thus leading to chemoresistance. VE-821, a specific inhibitor of ATR, has been proven to suppress a variety of solid malignanci...

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Detalles Bibliográficos
Autores principales: Su, Haochen, Yuan, Yue, Tang, Jiatong, Zhang, Yixuan, Wu, Hao, Zhang, Yin, Liang, Jiawei, Wang, Lei, Zou, Xiaoping, Huang, Shuling, Zhang, Shu, Lv, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400920/
https://www.ncbi.nlm.nih.gov/pubmed/37517142
http://dx.doi.org/10.1016/j.tranon.2023.101743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400920/
https://www.ncbi.nlm.nih.gov/pubmed/37517142
http://dx.doi.org/10.1016/j.tranon.2023.101743

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