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Inducible Protein Degradation as a Strategy to Identify Phosphoprotein Phosphatase 6 Substrates in RAS-Mutant Colorectal Cancer Cells

Protein phosphorylation is an essential regulatory mechanism that controls most cellular processes, including cell cycle progression, cell division, and response to extracellular stimuli, among many others, and is deregulated in many diseases. Protein phosphorylation is coordinated by the opposing a...

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Detalles Bibliográficos
Autores principales: Mariano, Natasha C., Rusin, Scott F., Nasa, Isha, Kettenbach, Arminja N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400926/
https://www.ncbi.nlm.nih.gov/pubmed/37392812
http://dx.doi.org/10.1016/j.mcpro.2023.100614