The contributions of rare inherited and polygenic risk to ASD in multiplex families

Autism spectrum disorder (ASD) has a complex genetic architecture involving contributions from both de novo and inherited variation. Few studies have been designed to address the role of rare inherited variation or its interaction with common polygenic risk in ASD. Here, we performed whole-genome se...

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Detalles Bibliográficos
Autores principales: Cirnigliaro, Matilde, Chang, Timothy S., Arteaga, Stephanie A., Pérez-Cano, Laura, Ruzzo, Elizabeth K., Gordon, Aaron, Bicks, Lucy K., Jung, Jae-Yoon, Lowe, Jennifer K., Wall, Dennis P., Geschwind, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400943/
https://www.ncbi.nlm.nih.gov/pubmed/37506195
http://dx.doi.org/10.1073/pnas.2215632120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400943/
https://www.ncbi.nlm.nih.gov/pubmed/37506195
http://dx.doi.org/10.1073/pnas.2215632120

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