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Optimized protocol for the generation of functional human induced-pluripotent-stem-cell-derived dopaminergic neurons
Generation of functional human dopaminergic (DA) neurons from human induced pluripotent stem cells (hiPSCs) is a crucial tool for modeling dopamine-related human diseases and cell replacement therapies. Here, we present a protocol to combine neuralizing transcription factor (NGN2) programming and DA...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400954/ https://www.ncbi.nlm.nih.gov/pubmed/37515763 http://dx.doi.org/10.1016/j.xpro.2023.102486 |