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Optimized protocol for the generation of functional human induced-pluripotent-stem-cell-derived dopaminergic neurons

Generation of functional human dopaminergic (DA) neurons from human induced pluripotent stem cells (hiPSCs) is a crucial tool for modeling dopamine-related human diseases and cell replacement therapies. Here, we present a protocol to combine neuralizing transcription factor (NGN2) programming and DA...

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Detalles Bibliográficos
Autores principales: Sheta, Razan, Teixeira, Maxime, Idi, Walid, Oueslati, Abid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400954/
https://www.ncbi.nlm.nih.gov/pubmed/37515763
http://dx.doi.org/10.1016/j.xpro.2023.102486