Nsp3-N interactions are critical for SARS-CoV-2 fitness and virulence

SARS-CoV-2, the causative agent of COVID-19 encodes at least 16 nonstructural proteins of variably understood function. Nsp3, the largest nonstructural protein contains several domains, including a SARS-unique domain (SUD), which occurs only in Sarbecovirus. The SUD has a role in preferentially enha...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Pengfei, Xue, Biyun, Schnicker, Nicholas J., Wong, Lok-Yin Roy, Meyerholz, David K., Perlman, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400999/
https://www.ncbi.nlm.nih.gov/pubmed/37487098
http://dx.doi.org/10.1073/pnas.2305674120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400999/
https://www.ncbi.nlm.nih.gov/pubmed/37487098
http://dx.doi.org/10.1073/pnas.2305674120

Ejemplares similares