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Nsp3-N interactions are critical for SARS-CoV-2 fitness and virulence

SARS-CoV-2, the causative agent of COVID-19 encodes at least 16 nonstructural proteins of variably understood function. Nsp3, the largest nonstructural protein contains several domains, including a SARS-unique domain (SUD), which occurs only in Sarbecovirus. The SUD has a role in preferentially enha...

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Detalles Bibliográficos
Autores principales:	Li, Pengfei, Xue, Biyun, Schnicker, Nicholas J., Wong, Lok-Yin Roy, Meyerholz, David K., Perlman, Stanley
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400999/ https://www.ncbi.nlm.nih.gov/pubmed/37487098 http://dx.doi.org/10.1073/pnas.2305674120

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