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Fast protein folding is governed by memory-dependent friction
When described by a low-dimensional reaction coordinate, the folding rates of most proteins are determined by a subtle interplay between free-energy barriers, which separate folded and unfolded states, and friction. While it is commonplace to extract free-energy profiles from molecular trajectories,...
Autores principales: | Dalton, Benjamin A., Ayaz, Cihan, Kiefer, Henrik, Klimek, Anton, Tepper, Lucas, Netz, Roland R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401029/ https://www.ncbi.nlm.nih.gov/pubmed/37490533 http://dx.doi.org/10.1073/pnas.2220068120 |
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