Low T-cell reactivity to TDP-43 peptides in ALS

BACKGROUND: Dysregulation of the immune system in amyotrophic lateral sclerosis (ALS) includes changes in T-cells composition and infiltration of T cells in the brain and spinal cord. Recent studies have shown that cytotoxic T cells can directly induce motor neuron death in a mouse model of ALS and...

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Detalles Bibliográficos
Autores principales: Ramachandran, Swetha, Grozdanov, Veselin, Leins, Bianca, Kandler, Katharina, Witzel, Simon, Mulaw, Medhanie, Ludolph, Albert C., Weishaupt, Jochen H., Danzer, Karin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401033/
https://www.ncbi.nlm.nih.gov/pubmed/37545536
http://dx.doi.org/10.3389/fimmu.2023.1193507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401033/
https://www.ncbi.nlm.nih.gov/pubmed/37545536
http://dx.doi.org/10.3389/fimmu.2023.1193507

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