Synthetic Epigenetic Reprogramming of Mesenchymal to Epithelial States Using the CRISPR/dCas9 Platform in Triple Negative Breast Cancer

Epithelial‐mesenchymal transition (EMT) is a reversible transcriptional program invoked by cancer cells to drive cancer progression. Transcription factor ZEB1 is a master regulator of EMT, driving disease recurrence in poor‐outcome triple negative breast cancers (TNBCs). Here, this work silences ZEB...

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Detalles Bibliográficos
Autores principales: Waryah, Charlene, Cursons, Joseph, Foroutan, Momeneh, Pflueger, Christian, Wang, Edina, Molania, Ramyar, Woodward, Eleanor, Sorolla, Anabel, Wallis, Christopher, Moses, Colette, Glas, Irina, Magalhães, Leandro, Thompson, Erik W., Fearnley, Liam G., Chaffer, Christine L., Davis, Melissa, Papenfuss, Anthony T., Redfern, Andrew, Lister, Ryan, Esteller, Manel, Blancafort, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401103/
https://www.ncbi.nlm.nih.gov/pubmed/37217832
http://dx.doi.org/10.1002/advs.202301802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401103/
https://www.ncbi.nlm.nih.gov/pubmed/37217832
http://dx.doi.org/10.1002/advs.202301802

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