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Donafenib and GSK‐J4 Synergistically Induce Ferroptosis in Liver Cancer by Upregulating HMOX1 Expression

Hepatocellular carcinoma (HCC) is one of the most lethal cancers worldwide. Donafenib is a multi‐receptor tyrosine kinase inhibitor approved for the treatment of patients with advanced HCC, but its clinical effect is very limited. Here, through integrated screening of a small‐molecule inhibitor libr...

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Detalles Bibliográficos
Autores principales: Zheng, Chenyang, Zhang, Bo, Li, Yunyun, Liu, Kejia, Wei, Wei, Liang, Shuhang, Guo, Hongrui, Ma, Kun, Liu, Yao, Wang, Jiabei, Liu, Lianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401117/
https://www.ncbi.nlm.nih.gov/pubmed/37330650
http://dx.doi.org/10.1002/advs.202206798