Paeonol alleviates neuropathic pain by modulating microglial M1 and M2 polarization via the RhoA/p38MAPK signaling pathway

BACKGROUND: This study aimed to investigate the potential mechanism of paeonol in the treatment of neuropathic pain. METHODS: Relevant mechanisms were explored through microglial pseudotime analysis and the use of specific inhibitors in cell experiments. In animal experiments, 32 SD rats were random...

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Detalles Bibliográficos
Autores principales: Li, Xin, Shi, Huimei, Zhang, Di, Jing, Bei, Chen, Zhenni, Zheng, Yachun, Chang, Shiquan, Gao, Li, Zhao, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401133/
https://www.ncbi.nlm.nih.gov/pubmed/37032648
http://dx.doi.org/10.1111/cns.14211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401133/
https://www.ncbi.nlm.nih.gov/pubmed/37032648
http://dx.doi.org/10.1111/cns.14211

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