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Paeonol alleviates neuropathic pain by modulating microglial M1 and M2 polarization via the RhoA/p38MAPK signaling pathway
BACKGROUND: This study aimed to investigate the potential mechanism of paeonol in the treatment of neuropathic pain. METHODS: Relevant mechanisms were explored through microglial pseudotime analysis and the use of specific inhibitors in cell experiments. In animal experiments, 32 SD rats were random...
Autores principales: | Li, Xin, Shi, Huimei, Zhang, Di, Jing, Bei, Chen, Zhenni, Zheng, Yachun, Chang, Shiquan, Gao, Li, Zhao, Guoping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401133/ https://www.ncbi.nlm.nih.gov/pubmed/37032648 http://dx.doi.org/10.1111/cns.14211 |
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