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14, 15‐EET alleviates neurological impairment through maintaining mitochondrial dynamics equilibrium via AMPK/SIRT1/FoxO1 signal pathways in mice with cerebral ischemia reperfusion

AIM: To explore whether 14, 15‐EET regulates mitochondrial dynamics to exert neuroprotective effects after cerebral ischemia–reperfusion and its underlying mechanisms. METHODS: The mouse middle cerebral artery occlusion reperfusion model was used to observe brain infarct volume and neuronal apoptosi...

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Detalles Bibliográficos
Autores principales: Tang, Jing, Chen, Yiang, Li, Jinyuan, Yan, Shuo, Wang, Zenan, Deng, Xinyu, Feng, Ke, Zhang, Yanshuo, Chen, Chunrong, Geng, Huixia, Wang, Yanming, Wang, Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401172/
https://www.ncbi.nlm.nih.gov/pubmed/37017405
http://dx.doi.org/10.1111/cns.14198