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Dysfunctional synaptic pruning by microglia correlates with cognitive impairment in sleep-deprived mice: Involvement of CX3CR1 signaling

Microglia are involved in sleep/wake cycles and the response to sleep loss. Synaptic pruning by microglia is necessary for central nervous system circuit refinement and contributes to cognitive function. Here, we investigated whether and how microglia-mediated synaptic pruning may be involved in cog...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Ling, Hanyi, He, Hui, Hu, Nan, Xiao, Lin, Zhang, Yue, Xie, Lei, You, Zili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401339/
https://www.ncbi.nlm.nih.gov/pubmed/37547773
http://dx.doi.org/10.1016/j.ynstr.2023.100553