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Glucocorticoid receptors regulate central amygdala GABAergic synapses in Marchigian-Sardinian alcohol-preferring rats

Impairments in the function of the hypothalamic-pituitary-adrenal (HPA) axis and enhanced glucocorticoid receptor (GR) activity in the central amygdala (CeA) are critical mechanisms in the pathogenesis of alcohol use disorder (AUD). The GR antagonist mifepristone attenuates craving in AUD patients,...

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Detalles Bibliográficos
Autores principales: Khom, Sophia, Borgonetti, Vittoria, Vozella, Valentina, Kirson, Dean, Rodriguez, Larry, Gandhi, Pauravi, Bianchi, Paula Cristina, Snyder, Angela, Vlkolinsky, Roman, Bajo, Michal, Oleata, Christopher S., Ciccocioppo, Roberto, Roberto, Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401345/
https://www.ncbi.nlm.nih.gov/pubmed/37547774
http://dx.doi.org/10.1016/j.ynstr.2023.100547