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Cellular delivery of relaxin-2 mRNA as a potential treatment for kidney fibrosis

Renal fibrosis is a pathological feature of chronic kidney disease and its progression correlates with kidney function impairment. Since there are currently no specific therapies for renal fibrosis, we explored whether inducing local production of the anti-fibrotic molecule relaxin-2 in kidney cells...

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Detalles Bibliográficos
Autores principales: Ding, Chenguang, Wang, Bo, Lai, Xiang Feng, Guo, Yingcong, Tesch, Greg, Ding, Xiaoming, Zheng, Jin, Tian, PuXun, Ricardo, Sharon, Shen, Hsin-Hui, Xue, Wujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401360/
https://www.ncbi.nlm.nih.gov/pubmed/37545557
http://dx.doi.org/10.1016/j.mtbio.2023.100716