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Cellular delivery of relaxin-2 mRNA as a potential treatment for kidney fibrosis
Renal fibrosis is a pathological feature of chronic kidney disease and its progression correlates with kidney function impairment. Since there are currently no specific therapies for renal fibrosis, we explored whether inducing local production of the anti-fibrotic molecule relaxin-2 in kidney cells...
Autores principales: | Ding, Chenguang, Wang, Bo, Lai, Xiang Feng, Guo, Yingcong, Tesch, Greg, Ding, Xiaoming, Zheng, Jin, Tian, PuXun, Ricardo, Sharon, Shen, Hsin-Hui, Xue, Wujun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401360/ https://www.ncbi.nlm.nih.gov/pubmed/37545557 http://dx.doi.org/10.1016/j.mtbio.2023.100716 |
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