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Generation of a human haploid neural stem cell line for genome-wide genetic screening

BACKGROUND: Haploid embryonic stem cells (haESCs) have been established in many species. Differentiated haploid cell line types in mammals are lacking due to spontaneous diploidization during differentiation that compromises lineage-specific screens. AIM: To derive human haploid neural stem cells (h...

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Detalles Bibliográficos
Autores principales: Wang, Hai-Song, Ma, Xin-Rui, Niu, Wen-Bin, Shi, Hao, Liu, Yi-Dong, Ma, Ning-Zhao, Zhang, Nan, Jiang, Zi-Wei, Sun, Ying-Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401418/
https://www.ncbi.nlm.nih.gov/pubmed/37545755
http://dx.doi.org/10.4252/wjsc.v15.i7.734