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Klotho: A new therapeutic target in diabetic retinopathy?

Klotho (Kl) is considered an antiaging gene, mainly for the inhibition of the insulin-like growth factor-1 signaling. Kl exists as full-length transmembrane, which acts as co-receptor for fibroblast growth factor receptor, and in soluble forms (sKl). The sKl may exert pleiotropic effects on organs a...

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Detalles Bibliográficos
Autores principales: Puddu, Alessandra, Maggi, Davide Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401458/
https://www.ncbi.nlm.nih.gov/pubmed/37547589
http://dx.doi.org/10.4239/wjd.v14.i7.1027