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Adenosine monophosphate‐activated protein kinase is elevated in human cachectic muscle and prevents cancer‐induced metabolic dysfunction in mice

BACKGROUND: Metabolic dysfunction and cachexia are associated with poor cancer prognosis. With no pharmacological treatments, it is crucial to define the molecular mechanisms causing cancer‐induced metabolic dysfunction and cachexia. Adenosine monophosphate‐activated protein kinase (AMPK) connects m...

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Detalles Bibliográficos
Autores principales: Raun, Steffen H., Ali, Mona S., Han, Xiuqing, Henríquez‐Olguín, Carlos, Pham, T.C. Phung, Meneses‐Valdés, Roberto, Knudsen, Jonas R., Willemsen, Anna C.H., Larsen, Steen, Jensen, Thomas E., Langen, Ramon, Sylow, Lykke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401533/
https://www.ncbi.nlm.nih.gov/pubmed/37194385
http://dx.doi.org/10.1002/jcsm.13238