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Adiposity is associated with widespread transcriptional changes and downregulation of longevity pathways in aged skeletal muscle

BACKGROUND: Amongst healthy older people, a number of correlates of impaired skeletal muscle mass and function have been defined. Although the prevalence of obesity is increasing markedly in this age group, information is sparse about the particular impacts of obesity on ageing skeletal muscle or th...

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Detalles Bibliográficos
Autores principales: Burton, Mark A., Antoun, Elie, Garratt, Emma S., Westbury, Leo, Baczynska, Alica, Dennison, Elaine M., Harvey, Nicholas C., Cooper, Cyrus, Patel, Harnish P., Godfrey, Keith M., Lillycrop, Karen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401538/
https://www.ncbi.nlm.nih.gov/pubmed/37199333
http://dx.doi.org/10.1002/jcsm.13255