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Skeletal muscle analysis of cancer patients reveals a potential role for carnosine in muscle wasting

BACKGROUND: Muscle wasting during cancer cachexia is mediated by protein degradation via autophagy and ubiquitin‐linked proteolysis. These processes are sensitive to changes in intracellular pH ([pH](i)) and reactive oxygen species, which in skeletal muscle are partly regulated by histidyl dipeptide...

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Detalles Bibliográficos
Autores principales: Posa, Dheeraj Kumar, Miller, Janice, Hoetker, David, Ramage, Michael I., Gao, Hong, Zhao, Jingjing, Doelling, Benjamin, Bhatnagar, Aruni, Wigmore, Stephen J., Skipworth, Richard J.E., Baba, Shahid P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401540/
https://www.ncbi.nlm.nih.gov/pubmed/37199284
http://dx.doi.org/10.1002/jcsm.13258