Cargando…
Skeletal muscle analysis of cancer patients reveals a potential role for carnosine in muscle wasting
BACKGROUND: Muscle wasting during cancer cachexia is mediated by protein degradation via autophagy and ubiquitin‐linked proteolysis. These processes are sensitive to changes in intracellular pH ([pH](i)) and reactive oxygen species, which in skeletal muscle are partly regulated by histidyl dipeptide...
Autores principales: | Posa, Dheeraj Kumar, Miller, Janice, Hoetker, David, Ramage, Michael I., Gao, Hong, Zhao, Jingjing, Doelling, Benjamin, Bhatnagar, Aruni, Wigmore, Stephen J., Skipworth, Richard J.E., Baba, Shahid P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401540/ https://www.ncbi.nlm.nih.gov/pubmed/37199284 http://dx.doi.org/10.1002/jcsm.13258 |
Ejemplares similares
-
Metabolic Pathways for Removing Reactive Aldehydes are Diminished in Atrophic Muscle During Heart Failure
por: Chaudhari, Mamata, et al.
Publicado: (2023) -
Carnosine Supplementation Enhances Post Ischemic Hind Limb Revascularization
por: Boakye, Adjoa A., et al.
Publicado: (2019) -
Urinary Levels of the Acrolein Conjugates of Carnosine Are Associated with Cardiovascular Disease Risk
por: O’Toole, Timothy E., et al.
Publicado: (2021) -
Intracellular pH Regulation of Skeletal Muscle in the Milieu of Insulin Signaling
por: Posa, Dheeraj Kumar, et al.
Publicado: (2020) -
Effect of muscle fibre types and carnosine levels on the expression of carnosine-related genes in pig skeletal muscle
por: Kalbe, Claudia, et al.
Publicado: (2023)