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SPSB1‐mediated inhibition of TGF‐β receptor‐II impairs myogenesis in inflammation

BACKGROUND: Sepsis‐induced intensive care unit‐acquired weakness (ICUAW) features profound muscle atrophy and attenuated muscle regeneration related to malfunctioning satellite cells. Transforming growth factor beta (TGF‐β) is involved in both processes. We uncovered an increased expression of the T...

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Detalles Bibliográficos
Autores principales: Li, Yi, Dörmann, Niklas, Brinschwitz, Björn, Kny, Melanie, Martin, Elisa, Bartels, Kirsten, Li, Ning, Giri, Priyanka Voori, Schwanz, Stefan, Boschmann, Michael, Hille, Susanne, Fielitz, Britta, Wollersheim, Tobias, Grunow, Julius, Felix, Stephan B., Weber‐Carstens, Steffen, Luft, Friedrich C., Müller, Oliver J., Fielitz, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401548/
https://www.ncbi.nlm.nih.gov/pubmed/37209006
http://dx.doi.org/10.1002/jcsm.13252