The Double-Layered Structure of Amyloid-β Assemblage on GM1-Containing Membranes Catalytically Promotes Fibrillization

[Image: see text] Alzheimer’s disease (AD) is associated with progressive accumulation of amyloid-β (Aβ) cross-β fibrils in the brain. Aβ species tightly associated with GM1 ganglioside, a glycosphingolipid abundant in neuronal membranes, promote amyloid fibril formation; therefore, they could be at...

Descripción completa

Detalles Bibliográficos
Autores principales: Yagi-Utsumi, Maho, Itoh, Satoru G., Okumura, Hisashi, Yanagisawa, Katsuhiko, Kato, Koichi, Nishimura, Katsuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401643/
https://www.ncbi.nlm.nih.gov/pubmed/37482658
http://dx.doi.org/10.1021/acschemneuro.3c00192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401643/
https://www.ncbi.nlm.nih.gov/pubmed/37482658
http://dx.doi.org/10.1021/acschemneuro.3c00192

Ejemplares similares