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The Double-Layered Structure of Amyloid-β Assemblage on GM1-Containing Membranes Catalytically Promotes Fibrillization

[Image: see text] Alzheimer’s disease (AD) is associated with progressive accumulation of amyloid-β (Aβ) cross-β fibrils in the brain. Aβ species tightly associated with GM1 ganglioside, a glycosphingolipid abundant in neuronal membranes, promote amyloid fibril formation; therefore, they could be at...

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Detalles Bibliográficos
Autores principales:	Yagi-Utsumi, Maho, Itoh, Satoru G., Okumura, Hisashi, Yanagisawa, Katsuhiko, Kato, Koichi, Nishimura, Katsuyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401643/ https://www.ncbi.nlm.nih.gov/pubmed/37482658 http://dx.doi.org/10.1021/acschemneuro.3c00192

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