Structure–Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT(2A) Receptor Agonists

[Image: see text] Serotonergic psychedelics are described to have activation of the serotonin 2A receptor (5-HT(2A)) as their main pharmacological action. Despite their relevance, the molecular mechanisms underlying the psychedelic effects induced by certain 5-HT(2A) agonists remain elusive. One of...

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Detalles Bibliográficos
Autores principales: Pottie, Eline, Poulie, Christian B. M., Simon, Icaro A., Harpsøe, Kasper, D’Andrea, Laura, Komarov, Igor V., Gloriam, David E., Jensen, Anders A., Kristensen, Jesper L., Stove, Christophe P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401645/
https://www.ncbi.nlm.nih.gov/pubmed/37474114
http://dx.doi.org/10.1021/acschemneuro.3c00267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401645/
https://www.ncbi.nlm.nih.gov/pubmed/37474114
http://dx.doi.org/10.1021/acschemneuro.3c00267

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