Cargando…

ALS Variants of Annexin A11’s Proline-Rich Domain Impair Its S100A6-Mediated Fibril Dissolution

[Image: see text] Mutations in the proline-rich domain (PRD) of annexin A11 are linked to amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease, and generate abundant neuronal A11 inclusions by an unknown mechanism. Here, we demonstrate that recombinant A11-PRD and its ALS-associate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shihora, Aman, Elias, Ruben D., Hammond, John A., Ghirlando, Rodolfo, Deshmukh, Lalit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401653/ https://www.ncbi.nlm.nih.gov/pubmed/37433222 http://dx.doi.org/10.1021/acschemneuro.3c00169

Ejemplares similares

Phase Separation and Fibrillization of Human Annexin A7 Are Mediated by Its Proline-Rich Domain
por: Yu, Chenrong, et al.
Publicado: (2023)

Reversible phase separation of ESCRT protein ALIX through tyrosine phosphorylation
por: Elias, Ruben D., et al.
Publicado: (2023)

The proline-rich domain of MML-1 is biologically important but not required for localization to target promoters
por: Ceballos, Ainhoa, et al.
Publicado: (2021)

The proline-rich domain of tau plays a role in interactions with actin
por: He, Hai Jin, et al.
Publicado: (2009)

Proline/serine‐rich coiled‐coil protein 1 inhibits macrophage inflammation and delays atherosclerotic progression by binding to Annexin A2
por: Pan, Hangyu, et al.
Publicado: (2023)

Tryptophan-Rich and Proline-Rich Antimicrobial Peptides
por: Mishra, Awdhesh Kumar, et al.
Publicado: (2018)

The proline-rich domain promotes Tau liquid–liquid phase separation in cells
por: Zhang, Xuemei, et al.
Publicado: (2020)

Role of the proline-rich disordered domain of DROSHA in intronic microRNA processing
por: Son, Soomin, et al.
Publicado: (2023)

The p11/S100A10 Light Chain of Annexin A2 Is Dispensable for Annexin A2 Association to Endosomes and Functions in Endosomal Transport
por: Morel, Etienne, et al.
Publicado: (2007)

Diclofenac-proline nano-co-crystal development, characterization, in vitro dissolution and diffusion study
por: Nugrahani, Ilma, et al.
Publicado: (2020)

The SH3 domain of p56lck binds to proline-rich sequences in the cytoplasmic domain of CD2
Publicado: (1996)

Tau phosphorylation regulates the interaction between BIN1’s SH3 domain and Tau’s proline-rich domain
por: Sottejeau, Yoann, et al.
Publicado: (2015)

Crystal structure of human profilaggrin S100 domain and identification of target proteins annexin II, stratifin and hsp27
por: Bunick, Christopher G, et al.
Publicado: (2015)

COORDINATED ACTIVATION OF THE RAC-GAP β2-CHIMAERIN BY AN ATYPICAL PROLINE-RICH DOMAIN AND DIACYLGLYCEROL
por: Gutierrez-Uzquiza, Alvaro, et al.
Publicado: (2013)

Phosphorylation of the proline-rich domain of WAVE3 drives its oncogenic activity in breast cancer
por: Kansakar, Urna, et al.
Publicado: (2021)

Co-Crystals of Resveratrol and Polydatin with L-Proline: Crystal Structures, Dissolution Properties, and In Vitro Cytotoxicities
por: Lou, Yijie, et al.
Publicado: (2021)

The resealing factor S100A11 interacts with annexins and extended synaptotagmin-1 in the course of plasma membrane wound repair
por: Ashraf, Arsila P. K., et al.
Publicado: (2022)

Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer
por: Lee, Kyung-min, et al.
Publicado: (2020)

Maintenance of a Vertebrate Constitutive Heterochromatin Domain by a Dicer-dependent Mechanism
por: Giles, Keith E., et al.
Publicado: (2009)

Importance of the proline-rich multimerization domain on the oligomerization and nucleic acid binding properties of HIV-1 Vif
por: Bernacchi, Serena, et al.
Publicado: (2011)

WH2 and proline‐rich domains of WASP‐family proteins collaborate to accelerate actin filament elongation
por: Bieling, Peter, et al.
Publicado: (2017)

Slow Dissolution Kinetics of Model Peptide Fibrils
por: Koder Hamid, Mona, et al.
Publicado: (2020)

Susceptibility to Dental Caries and the Salivary Proline-Rich Proteins
por: Levine, Martin
Publicado: (2011)

Effects of Lipidation on a Proline-Rich Antibacterial Peptide
por: Armas, Federica, et al.
Publicado: (2021)

Upregulation of proline rich 11 is an independent unfavorable prognostic factor for survival of tongue squamous cell carcinoma patients
por: Wang, Chunyang, et al.
Publicado: (2017)

The Cell Wall PAC (Proline-Rich, Arabinogalactan Proteins, Conserved Cysteines) Domain-Proteins Are Conserved in the Green Lineage
por: Nguyen-Kim, Huan, et al.
Publicado: (2020)

Publisher Correction: Phosphorylation of the proline-rich domain of WAVE3 drives its oncogenic activity in breast cancer
por: Kansakar, Urna, et al.
Publicado: (2021)

Annexin A2 complexes with S100 proteins: structure, function and pharmacological manipulation
por: Liu, Yidong, et al.
Publicado: (2015)

Proline Rich Motifs as Drug Targets in Immune Mediated Disorders
por: Srinivasan, Mythily, et al.
Publicado: (2012)

The Mechanism of Inhibition of Protein Synthesis by the Proline-Rich Peptide Oncocin
por: Roy, Raktim N, et al.
Publicado: (2015)

Proline-Rich Protein Tyrosine Kinase 2 in Inflammation and Cancer
por: Zhu, Xiangdong, et al.
Publicado: (2018)

Effect of proline rich 15-deficiency on trophoblast viability and survival
por: Gates, Katherine C., et al.
Publicado: (2017)

Direct evaluation of the antioxidant properties of salivary proline-rich proteins
por: Komatsu, Tomoko, et al.
Publicado: (2020)

Inhibition of Intimal Thickening By PRH (Proline-Rich Homeodomain) in Mice
por: Reolizo, Lien M., et al.
Publicado: (2023)

Fluorine NMR study of proline-rich sequences using fluoroprolines
por: Sinnaeve, Davy, et al.
Publicado: (2021)

Interactions of the N- and C-Terminal SH3 Domains of Drosophila Drk with the Proline-Rich Peptides from Sos and Dos
por: Sayeesh, Pooppadi Maxin, et al.
Publicado: (2023)

Adaptation of an L-Proline Adenylation Domain to Use 4-Propyl-L-Proline in the Evolution of Lincosamide Biosynthesis
por: Kadlčík, Stanislav, et al.
Publicado: (2013)

MicroRNA-26b-5p suppresses the proliferation of tongue squamous cell carcinoma via targeting proline rich 11 (PRR11)
por: Yi, Liang, et al.
Publicado: (2021)

Synergistic Inhibition of Protein Fibrillation by Proline and Sorbitol: Biophysical Investigations
por: Choudhary, Sinjan, et al.
Publicado: (2016)

S100A11 protects against neuronal cell apoptosis induced by cerebral ischemia via inhibiting the nuclear translocation of annexin A1
por: Xia, Qian, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_v2423k1oqb8436d3igaa3jj9pm