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Multicomponent Oxidative Nitrile Thiazolidination Reaction for Selective Modification of N-terminal Dimethylation Posttranslational Modification

[Image: see text] Protein α-N-terminal dimethylation (Nme(2)) is an underexplored posttranslational modification (PTM) despite the increasing implications of α-N-terminal dimethylation in vital physiological and pathological processes across diverse species; thus, it is imperative to identify the si...

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Detalles Bibliográficos
Autores principales: Emenike, Benjamin, Donovan, Julia, Raj, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401698/
https://www.ncbi.nlm.nih.gov/pubmed/37486086
http://dx.doi.org/10.1021/jacs.3c02369