Imaging Saturation Transfer Difference (STD) NMR: Affinity and Specificity of Protein–Ligand Interactions from a Single NMR Sample

[Image: see text] We have combined saturation transfer difference NMR (STD NMR) with chemical shift imaging (CSI) and controlled concentration gradients of small molecule ligands to develop imaging STD NMR, a new tool for the assessment of protein–ligand interactions. Our methodology allows the dete...

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Detalles Bibliográficos
Autores principales: Monaco, Serena, Angulo, Jesus, Wallace, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401705/
https://www.ncbi.nlm.nih.gov/pubmed/37487192
http://dx.doi.org/10.1021/jacs.3c02218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401705/
https://www.ncbi.nlm.nih.gov/pubmed/37487192
http://dx.doi.org/10.1021/jacs.3c02218

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