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Integrated NMR/Molecular Dynamics Determination of the Ensemble Conformation of a Thermodynamically Stable CUUG RNA Tetraloop

[Image: see text] Both experimental and theoretical structure determinations of RNAs have remained challenging due to the intrinsic dynamics of RNAs. We report here an integrated nuclear magnetic resonance/molecular dynamics (NMR/MD) structure determination approach to describe the dynamic structure...

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Detalles Bibliográficos
Autores principales: Oxenfarth, Andreas, Kümmerer, Felix, Bottaro, Sandro, Schnieders, Robbin, Pinter, György, Jonker, Hendrik R. A., Fürtig, Boris, Richter, Christian, Blackledge, Martin, Lindorff-Larsen, Kresten, Schwalbe, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401711/
https://www.ncbi.nlm.nih.gov/pubmed/37479220
http://dx.doi.org/10.1021/jacs.3c03578