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Semaphorin 3 C enhances putative cancer stemness and accelerates peritoneal dissemination in pancreatic cancer

PURPOSE: Semaphorins, axon guidance cues in neuronal network formation, have been implicated in cancer progression. We previously identified semaphorin 3 C (SEMA3C) as a secreted protein overexpressed in pancreatic ductal adenocarcinoma (PDAC). We, therefore, hypothesized that SEMA3C supports PDAC p...

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Detalles Bibliográficos
Autores principales: Tomizawa, Satoshi, Takano, Shigetsugu, Eto, Ryotaro, Takayashiki, Tsukasa, Kuboki, Satoshi, Ohtsuka, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401755/
https://www.ncbi.nlm.nih.gov/pubmed/37537633
http://dx.doi.org/10.1186/s12935-023-03008-3